CONP Portal | Dataset


BigBrain dataset - Raw Data
Creators: BigBrain project
Contact: info@bigbrainproject.org
Licenses: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License
Version: 1.0
Modalities: histology
Formats: MINC TIFF
Size: 937.3 GB
No of Files: 7367
No of Subjects: 1
Primary Publication: BigBrain: an ultrahigh-resolution 3D human brain model. Science.
Project Landing Page: https://bigbrainproject.org
Metadata file: DATS.json
Is About: Homo sapiens, adult
Description:
The BigBrain raw data dataset contains post-mortem MRI aligned to the block faces and raw sections from the BigBrain dataset, a digitized reconstruction of high-resolution histological sections of the brain of a 65 years old man with no history of neurological or psychiatric diseases. The BigBrain dataset is the result of a collaborative effort between the teams of Dr. Katrin Amunts and Dr. Karl Zilles (Forschungszentrum Jülich) and Dr. Alan Evans (Montreal Neurological Institute). For more information please visit the BigBrain Project website [https://bigbrainproject.org]

Dataset README information

README.md

BigBrain 3D ROIs

BigBrain

The BigBrain is the brain of a 65 years old man with no neurological or psychiatric
diseases in clinical records at time of death. The brain was embedded in parafin and
sectioned in 7404 coronal histological sections (20 microns), stained for cell bodies.
The BigBrain is the digitized reconstruction of the hi-res histological sections
(20 microns isotropic).

Dataset content

This dataset contains the post-mortem MRI aligned to the block faces and raw sections
from the BigBrain published in the BigBrain Project website.

The raw sections are available in tiff format. This MRI dataset is not in the aligned
histological space. Use the MRI in the 2015 release itself.
A few raw sections at 1-micron are available, unaligned as these have been rescanned, so not
aligned to the other raw images at 10-micron in the MINC and TIFF folders.

Reference and more information

The BigBrain dataset is the result of a collaborative effort between the
teams of Dr. Katrin Amunts and Dr. Karl Zilles (Forschungszentrum Jülich)
and Dr. Alan Evans (Montreal Neurological Institute).

Amunts, K. et al.: "BigBrain: An Ultrahigh-Resolution 3D Human
Brain Model", Science (2013) 340 no. 6139 1472-1475, June 2013.
https://www.sciencemag.org/content/340/6139/1472.abstract

For more information please visit the BigBrain Project website.

Download Using DataLad

CircleCI status

The following instructions require a basic understanding of UNIX/LINUX command lines. A subset of open datasets on the Portal are also available through a browser-based download button. The instructions below regard dataset download with the use of DataLad. To install DataLad on your system, please refer to the install section of the DataLad Handbook .

Note: For maximum compatibility with conp-dataset, the CONP recommends versions 3.12+ of Python, 10.20241202+ of git-annex, and 1.1.4+ of datalad.

1) Initiate the CONP dataset

Run the following command in the directory where you want the CONP dataset (conp-dataset) to be installed:

2) Install the BigBrain_Raw_Data dataset

To install the BigBrain_Raw_Data dataset, run the following commands to move into the "projects" subdirectory under the "conp-dataset" directory (created in the previous step) and run datalad install:

3) Download data from the BigBrain_Raw_Data dataset

Now that the dataset has been installed, go into the BigBrain_Raw_Data dataset directory.

The files visible after installing the dataset but before downloading (in the next step) are symbolic links and need to be downloaded manually using the datalad get command:

If you run datalad get * command, all the files available in the dataset directory will be downloaded.


For more information on how DataLad works, please visit the DataLad Handbook documentation.