CONP Portal | Dataset
Ontario Neurodegenerative Disease Research Initiative (ONDRI): Foundational Study Longitudinal Data - Release 2.0
Is About: | Homo sapiens |
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Acknowledges: | Ontario Brain Institute, Ontario Neurodegenerative Disease Research Initiative participants, their study partners, and their families, Government of Ontario, The Temerty Family Foundation, Participating hospital and research institute foundations, including the Baycrest Foundation, Bruyère Research Institute, Centre for Addiction and Mental Health Foundation, London Health Sciences Foundation, McMaster University Faculty of Health Sciences, Ottawa Brain and Mind Research Institute, Queen's University Faculty of Health Sciences, Providence Care (Kingston), Sunnybrook Health Sciences Foundation, St. Michael's Hospital, the Thunder Bay Regional Health Sciences Centre, the University of Ottawa Faculty of Medicine, and the Windsor/Essex County ALS Association. |
Spatial Coverage: | Canada |
Other Dates: | Start Date: 2014-07-07 00:00:00 -- End Date: 2018-03-31 00:00:00 |
Description:
Dataset README information
Ontario Neurodegenerative Disease Research Initiative (ONDRI): Foundational Study Longitudinal Data - Release 2.0
Dr. Mario Masellis, Dr. Douglas Munoz, Dr. Michael Strong, Dr. Richard Swartz, ONDRI study team
Overview
ONDRI’s Foundational Study includes data from 520 people living with Alzheimer’s disease, mild cognitive impairment, Parkinson’s disease, amyotrophic lateral sclerosis, frontotemporal dementia, or cerebrovascular disease, along with their care partners. Detailed clinical, cognitive, genetic, gait, balance, eye tracking, retinal imaging, and neuroimaging assessments were performed that enable multi-modality within- and cross-disease analyses. Data were collected from 2014-18; then standardized, cleaned, and curated to facilitate open access and sharing. The release includes tabular data from all assessment platforms in addition to raw neuroimaging files. Baseline and Longitudinal data are now available for request.
Data organization
Data is organized into packages by Treatment Group, Timepoint, Imaging Data Type, Genomic Data Type, Spectral Domain Optical Coherence, Eyetracking, Neurophsychology and Clinical Data Collection Domain.
Access information
To gain access to Brain-CODE Controlled Data Release data, Study Investigators will submit requests via Data Release Portals at www.braincode.ca. These requests will be reviewed by the Brain-CODE Data Access Committee and the Brain-CODE Steering Committee. Learn more about these Committees in the Brain-CODE Governance Policy (https://braininstitute.ca/docs/Brain-CODE-Governance-Policy-version-FINAL.pdf).
Visit the Brain-CODE Knowledge Base to learn more about our data releases.
Citation
Sunderland KM, Beaton D, Arnott SR, Kleinstiver P, Kwan D, ,Lawrence-Dewar JM, Ramirez J, Tan B, Bartha R & Black SE (2022). Alzheimer's & Dementia. https://www.medrxiv.org/content/10.1101/2020.07.30.20165456v1.full-text
The following instructions require a basic understanding of UNIX/LINUX command lines. Future portal functionality may include downloads directly from the web browser. Dataset download is currently enabled through DataLad.
Note: The conp-dataset
requires version >=0.12.5 of DataLad
and version >=8.20200309 of git-annex.
To install DataLad on your system, please refer to the install section of the DataLad Handbook (installation via miniconda is recommended in order to obtain the latest version of DataLad).
1) Initiate the CONP dataset
To initiate the CONP dataset (conp-dataset
), run the following
command in the directory where you want CONP datasets to be installed:
datalad install https://github.com/CONP-PCNO/conp-dataset.git
2) Install the braincode_ONDRI_Foundation_Study_Baseline_Data_Release dataset
To install the dataset, go into the created conp-dataset directory and run
datalad install
on the dataset braincode_ONDRI_Foundation_Study_Baseline_Data_Release
:
cd conp-dataset
datalad install projects/braincode_ONDRI_Foundation_Study_Baseline_Data_Release
3) Download the braincode_ONDRI_Foundation_Study_Baseline_Data_Release dataset
Now that the DataLad dataset has been installed, go into the dataset
directory under projects/braincode_ONDRI_Foundation_Study_Baseline_Data_Release
.
cd projects/braincode_ONDRI_Foundation_Study_Baseline_Data_Release
Note that files visible in the dataset are symlinks and will need to be
downloaded manually using the
datalad get
command in the dataset directory:
datalad get <filepath>
Note, if you run datalad get *
command, all the files present
in the dataset directory will be downloaded.