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Ontario Neurodegenerative Disease Research Initiative (ONDRI): Foundational Study Longitudinal Data - Release 2.0
Creators: Ontario Brain Institute
Contact: Brain-CODE, datarelease@braincode.ca
Licenses: Refer to Brain-CODE Governance Policy
Version: 2.0
Formats: CSV TXT NIfTI
Size: 365.0 GB
No of Files: 889
No of Subjects: 520
Primary Publication: Characteristics of the Ontario Neurodegenerative Disease Research Initiative cohort. Alzheimer's & Dementia. 10.1002/alz.12632
Metadata file: DATS.json
Is About: Homo sapiens
Acknowledges: Ontario Brain Institute, Ontario Neurodegenerative Disease Research Initiative participants, their study partners, and their families, Government of Ontario, The Temerty Family Foundation, Participating hospital and research institute foundations, including the Baycrest Foundation, Bruyère Research Institute, Centre for Addiction and Mental Health Foundation, London Health Sciences Foundation, McMaster University Faculty of Health Sciences, Ottawa Brain and Mind Research Institute, Queen's University Faculty of Health Sciences, Providence Care (Kingston), Sunnybrook Health Sciences Foundation, St. Michael's Hospital, the Thunder Bay Regional Health Sciences Centre, the University of Ottawa Faculty of Medicine, and the Windsor/Essex County ALS Association.
Spatial Coverage: Canada
Other Dates: Start Date: 2014-07-07 00:00:00 -- End Date: 2018-03-31 00:00:00
Description:
Dr. Mario Masellis, Dr. Douglas Munoz, Dr. Michael Strong, Dr. Richard Swartz, ONDRI study team | ONDRI's Foundational Study includes data from 520 people living with Alzheimer's disease, mild cognitive impairment, Parkinson's disease, amyotrophic lateral sclerosis, frontotemporal dementia, or cerebrovascular disease, along with their care partners. Detailed clinical, cognitive, genetic, gait, balance, eye tracking, retinal imaging, and neuroimaging assessments were performed that enable multi-modality within- and cross-disease analyses. Data were collected from 2014-18; then standardized, cleaned, and curated to facilitate open access and sharing.

Dataset README information

README.md

Ontario Neurodegenerative Disease Research Initiative (ONDRI): Foundational Study Longitudinal Data - Release 2.0

Dr. Mario Masellis, Dr. Douglas Munoz, Dr. Michael Strong, Dr. Richard Swartz, ONDRI study team

Overview

ONDRI’s Foundational Study includes data from 520 people living with Alzheimer’s disease, mild cognitive impairment, Parkinson’s disease, amyotrophic lateral sclerosis, frontotemporal dementia, or cerebrovascular disease, along with their care partners. Detailed clinical, cognitive, genetic, gait, balance, eye tracking, retinal imaging, and neuroimaging assessments were performed that enable multi-modality within- and cross-disease analyses. Data were collected from 2014-18; then standardized, cleaned, and curated to facilitate open access and sharing. The release includes tabular data from all assessment platforms in addition to raw neuroimaging files. Baseline and Longitudinal data are now available for request.

Data organization

Data is organized into packages by Treatment Group, Timepoint, Imaging Data Type, Genomic Data Type, Spectral Domain Optical Coherence, Eyetracking, Neurophsychology and Clinical Data Collection Domain.

Access information

To gain access to Brain-CODE Controlled Data Release data, Study Investigators will submit requests via Data Release Portals at www.braincode.ca. These requests will be reviewed by the Brain-CODE Data Access Committee and the Brain-CODE Steering Committee. Learn more about these Committees in the Brain-CODE Governance Policy (https://braininstitute.ca/docs/Brain-CODE-Governance-Policy-version-FINAL.pdf).

Visit the Brain-CODE Knowledge Base to learn more about our data releases.

Citation

Sunderland KM, Beaton D, Arnott SR, Kleinstiver P, Kwan D, ,Lawrence-Dewar JM, Ramirez J, Tan B, Bartha R & Black SE (2022). Alzheimer's & Dementia. https://www.medrxiv.org/content/10.1101/2020.07.30.20165456v1.full-text